PEPFAR Analytics Hub

Comprehensive research by the Analytics Hub and KFF shows that PEPFAR’s impact extends well beyond its core mission of fighting HIV/AIDS, influencing a range of health and socio-economic outcomes in low- and middle-income countries (LMICs). Using rigorous methods, we analyzed data from 157 LMICs—including 90 PEPFAR-supported countries—spanning 1990 to 2018. Through difference-in-differences analysis, we compared outcomes before and after PEPFAR’s launch in 2004, uncovering significant spillover effects on maternal and child health (MCH), immunization rates, all-cause mortality, economic growth, and education.

Our analyses found that PEPFAR-supported countries saw marked improvements in childhood immunization rates for measles, DPT, and Hep B, as well as reductions in child and maternal mortality—without evidence of harm to other health sectors. All-cause mortality was 20% lower in PEPFAR recipient countries than what would have been expected without PEPFAR support, with the strongest effect seen in countries receiving higher PEPFAR funding and participating in the COP process. PEPFAR was also linked to increased GDP per capita growth and fewer children out of school. Together, these findings demonstrate PEPFAR’s broad and sustained development impact, reinforcing the value of continued investment in the program.

Our team continues to lead rigorous analysis to inform global discussions on the value of investing in the HIV response. By generating evidence on PEPFAR’s broader health and development impacts, we aim to support data-driven decision-making and sustain momentum toward equitable, long-term gains in global health

Key Partners

Convergent partnerships are at the heart of what we do. We are proud to partner with federal and state agencies, non-profit and advocacy organizations, philanthropic institutions, and universities to elevate social work leadership and to create equitable health and mental health care systems for all.